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streptococcus pneumoniae serotype 19f  (ATCC)


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    ATCC streptococcus pneumoniae serotype 19f
    Streptococcus Pneumoniae Serotype 19f, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 2885 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/serotype+19f/fda_document____cdrh_docs_slash_reviews_slash_k191967-105-0-8?v=ATCC
    Average 99 stars, based on 2885 article reviews
    streptococcus pneumoniae serotype 19f - by Bioz Stars, 2026-07
    99/100 stars

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    a ) Model of S pneumoniae pre-exposure and infection. Mice received escalating doses of RTX or Veh starting 21 days prior to the beginning of inoculation. 10 4 CFU of S pneumoniae (Serotype 19F, ATCC49619) was delivered on day 0 to expose mice, then 10 8 CFU was delivered on Day 9. Experiments took place 16 or 48h later. Gram stain shows S pneumoniae infection (purple, green arrows point to example of gram positive space) was greater in RTX compared to Veh. Scale bar=20µm. b) Bacterial recovery from lungs in untreated sensory neuron intact mice (Naïve), untreated sensory neuron ablated mice (Naive RTX), pre-exposed and infected sensory neuron intact (Veh) or pre-exposed and infected sensory neuron ablated mice (RTX). 16h: Naïve n=6, Naïve RTX: n=5, Veh: n=13, RTX: n=5. 48h: Naïve n=4, Naïve RTX: n=5, Veh: n=13, RTX: n=5. Two-way ANOVA with Holm-Sidak post hoc test. Data were pooled from three independent experiments. c) Quantification of B cell activating factor (BAFF), APRIL13 (TNFSF13), TNFα, IL-1β, IL-2, IL-6, IL-5, CXCL13, CCL5, CCL7 in sensory neuron intact (Veh n=7) and sensory neuron ablated (RTX, n=6) mice 16h following the final 10 9 CFU dose of S pneumoniae . Samples were analyzed with Luminex bead assay. IL-6 was re-run with ELISA. Two-sided t-test. Data were pooled from 2 independent experiments.

    Journal: bioRxiv

    Article Title: Sensory neurons regulate stimulus-dependent humoral immunity

    doi: 10.1101/2024.01.04.574231

    Figure Lengend Snippet: a ) Model of S pneumoniae pre-exposure and infection. Mice received escalating doses of RTX or Veh starting 21 days prior to the beginning of inoculation. 10 4 CFU of S pneumoniae (Serotype 19F, ATCC49619) was delivered on day 0 to expose mice, then 10 8 CFU was delivered on Day 9. Experiments took place 16 or 48h later. Gram stain shows S pneumoniae infection (purple, green arrows point to example of gram positive space) was greater in RTX compared to Veh. Scale bar=20µm. b) Bacterial recovery from lungs in untreated sensory neuron intact mice (Naïve), untreated sensory neuron ablated mice (Naive RTX), pre-exposed and infected sensory neuron intact (Veh) or pre-exposed and infected sensory neuron ablated mice (RTX). 16h: Naïve n=6, Naïve RTX: n=5, Veh: n=13, RTX: n=5. 48h: Naïve n=4, Naïve RTX: n=5, Veh: n=13, RTX: n=5. Two-way ANOVA with Holm-Sidak post hoc test. Data were pooled from three independent experiments. c) Quantification of B cell activating factor (BAFF), APRIL13 (TNFSF13), TNFα, IL-1β, IL-2, IL-6, IL-5, CXCL13, CCL5, CCL7 in sensory neuron intact (Veh n=7) and sensory neuron ablated (RTX, n=6) mice 16h following the final 10 9 CFU dose of S pneumoniae . Samples were analyzed with Luminex bead assay. IL-6 was re-run with ELISA. Two-sided t-test. Data were pooled from 2 independent experiments.

    Article Snippet: S. pneumoniae strain 49619 serotype 19F was purchased from ATCC.

    Techniques: Infection, Staining, Luminex, Enzyme-linked Immunosorbent Assay

    Comparative analysis of complement-mediated killing feature of anti-PhtD and anti-rPspA antibodies against pneumococcus strain ATCC49619. In the titer mentioned, serum antibodies can kill 50% of the pneumococci compared to the control group following complement cell activation and pore formation on the surface of pneumococci. ****: p<0.0001.

    Journal: Frontiers in Immunology

    Article Title: Development of a bivalent protein-based vaccine candidate against invasive pneumococcal diseases based on novel pneumococcal surface protein A in combination with pneumococcal histidine triad protein D

    doi: 10.3389/fimmu.2023.1187773

    Figure Lengend Snippet: Comparative analysis of complement-mediated killing feature of anti-PhtD and anti-rPspA antibodies against pneumococcus strain ATCC49619. In the titer mentioned, serum antibodies can kill 50% of the pneumococci compared to the control group following complement cell activation and pore formation on the surface of pneumococci. ****: p<0.0001.

    Article Snippet: E. coli BL21 (DE3) (Novagen) as an expression host and Streptococcus pneumoniae ATCC49619 (serotype 19F) (pneumococcus) were obtained from the bacterial collection of the Pasteur Institute of Iran.

    Techniques: Control, Activation Assay